Tru M.D. Support

$19.99

Tru M.D. Support, formulated by Ophthalmologists, provides the precise amounts of lutein and zeaxanthin, and other powerful antioxidant vitamins and minerals to support macular degeneration. † These key nutrients have shown superior results for healthy vision in the AREDS 2 trial conducted by the National Eye Institute.

TruGen3’s® TRU M.D. Support, formulated by Ophthalmologists, provides the precise amounts of lutein and zeaxanthin, and other powerful antioxidant vitamins and minerals to support macular degeneration. † These key nutrients have shown superior results for healthy vision in the AREDS 2 trial conducted by the National Eye Institute.

DISCUSSION

Oxidative and predominantly photo-oxidative stress are critical factors that influence eye health. The lens of the eye acts as a light filter for the retina and therefore, is continually exposed to photo-oxidative stress. In the retina, high levels of oxygen, light, and the more apparent blue light, create an ideal environment for the production of reactive oxygen species (ROS) that damage the membranes of visual cells. 1

Nature provided us with lutein and zeaxanthin, antioxidant carotenoids found in the human retina and macula. 2 Human eyes protect against natural levels of blue light, but that protection declines with age, as the light-capturing pigments lutein and zeaxanthin diminish from the retina pigment layer. 3 Evidence suggests that supplementing with lutein and zeaxanthin has a profound effect against photo induced damage to the lens and the retina. †2

The Lutein Antioxidant Supplementation Trial (LAST) of 90 men with multiple stages of macular degeneration, received 10 milligrams of lutein, 10 milligrams of lutein plus a multivitamin and mineral formula, or a placebo for twelve months. The men who received lutein or lutein with antioxidants achieved significant improvements in the quality of their vision. † 4 The Zeaxanthin and Visual Function Study (ZVF) showed improvement in high-contrast visual acuity compared to the placebo group. † 5

In addition to lutein and zeaxanthin, the healthy ocular lens is enhanced with the antioxidants vitamins C and E, which play a vital role in controlling the production of oxygen and light-induced free radicals. Zinc is an essential mineral that has been shown to support visual transduction in the rod cells. A double blind, placebo controlled trial of zinc supplementation, found a significant reduction in visual acuity loss associated with macular degeneration. †5

Though the supplement formula recommended by the original AREDS included beta-carotene as the only carotenoid, succeeding studies, like the AREDS-2, found that replacing beta-carotene with lutein and zeaxanthin significantly reduced the development of macular degeneration. † 6,7 TRU M.D. Support® formula contains the essential nutrients from the AREDS-2 study and reflects these positive results.

FORMULA (#5013)

Supplement Facts

Serving Size 2 Vegetarian capsules

Vitamin C (as ascorbic acid)………………………………………………………….……..500 mg
Vitamin E (as d-alpha tocopherol succinate)………………………………….…….270 mg Calcium…………………………………………………………………………………….…………..70 mg
Zinc (as zinc oxide)…………………………………………………………………….………….25 mg
Copper (as copper oxide)……………………………………………..………………………..2 mg
Lutein (from marigold flower extract)……………………….………………………….10 mg
Zeaxanthin (from marigold flower extract)……………………………………….…….2 mg

Other ingredients: Hypromellose, dicalcium phosphate, microcrystalline cellulose, vegetable stearate, silica and calcium silicate.

SUGGESTED USE

As a dietary supplement, adults take 2 capsules per day or as directed by your healthcare professional for macular degeneration support. †

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

REFERENCES
  1. Beatty S, et al. Macular pigment and age related macular degeneration Br J Ophthalmol 1999;83:867-877
  2. Roberts JE, Dennison J. The Photobiology of Lutein and Zeaxanthin in the Eye. J Ophthalmol. 2015;2015:687173.
  3. Coleman HR, Chan CC, Ferris FL, 3rd, et al. Age-related macular degeneration. Lancet. 2008;372(9652):1835- 45
  4. Richer S, et al. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 2004 Apr;75(4):216-30.
  5. Richer SP, et al. Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration: the Zeaxanthin and Visual Function Study (ZVF) FDA IND #78, 973. Optometry. 2011 Nov;82(11):667-680.e6.
  6. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled clinical trial of high-dose supplementation with vitamins C and E, beta-carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol. 2001;119(10)1417-1436.
  7. Chew EY, Clemons TE, Agrón E, et al; Age-Related Eye Disease Study Research Group. Long-term effects of vitamins C and E, ß-carotene, and zinc on age-related macular degeneration: AREDS report no. 35. Ophthalmology. 2013;120(8)1604-1611
  8. Age-Related Eye Disease Study 2 Research Group. (AREDS2) randomized clinical trial. JAMA. 2013 May15;309(19):2005-15.

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