Vitamin C and Zinc
Tru Immune Support contains healthful amounts of these two well-known immune-supporting nutrients.* Each of these is foundational to immune health.* For example, a meta-analysis determined that vitamin C was effective at supporting the health of 11,077 people who had the common cold.2* Dietary zinc also is critical for immunity. Even a mild deficiency can lead to weakened immune cell function.2* Studies have found zinc supplementation can support immune health in people encountering wintertime immune system challenges.2*
This botanical found in Tru Immune Support contains high amounts of polysaccharides, flavonoids, multiple trace minerals, and amino acids, all of which boast immune-supporting attributes.2* Astragalus keeps immune cells healthy.* Specifically, it maintains healthy humoral and adaptive immunity, leading to effective production of antibodies, supporting an optimal
CD4+/CD8+ ratio (a balanced ratio is an indication of optimal immune health), and shifting the Th1/Th2 immune response in favor of antiviral actions.3-6*
Astragalus may also increase the activation of natural killer cells,7 an important part of the body’s innate immune system.* Astragalus stabilizes immunity in cells exposed to the influenza virus.8* In animals exposed to the avian influenza virus, astragalus promotes a fast humoralimmune response.9* Furthermore, astragalus is involved in the health of respiratory cells,10 and research has found astragalus supports the lung health of human patients.11,12 As an antioxidant, it also supports lung health in conditions of oxidative stress.13*
EpiCor® is a dried fermentate produced from Saccharomyces cerevisiae, an immune-modulatingbaker’s yeast.* There are a number of good human studies showing EpiCor® acts as an antioxidant and supports a healthy immune response during exposure to colds and flus and during pollen season.14,17* EpiCor® strengthens mucosal immunity and increases levels of salivary secretory immunoglobulin A,14 a substance coating mucosal surfaces that acts like a
shield to stop unwanted substances from entering the body.* EpiCor® increases natural killer cells and supports a healthy inflammatory response.14,18* Three Generations of Truth in Nutrition
Olive Leaf Extract
Olive leaf extract contains phenolic compounds, especially oleuropein, an antioxidant shown to possess antimicrobial actions and to support a healthy inflammatory response.2* Research suggests that olive leaf reduces infectivity and replication by interacting with the protein of virus
particles, weakening viral actions.19* It also promotes a healthy immune response by encouraging phagocytosis, the ability of immune cells to engulf invaders,2 and it stimulates the production of natural killer cells.20* A randomized, placebo-controlled study of 32 high school athletes found olive leaf extract supported upper respiratory tract health.2121* Tru Immune Support contains olive leaf extract with a generous 16% oleuropein for optimal potency.*
Animal studies, cell culture experiments, and use in clinical practice suggest berberine supports a healthy inflammatory response and maintains immunity.* It promotes lung health in animals and the health of human airway cells.22-24* Berberine also stabilizes the inflammatory response during exposure to allergens.25* Additionally, berberine may be able to weaken bacteria that have formed biofilms,26* the colonization of bacteria in an area of the body or a surface. Biofilm formation protects the bacteria against antimicrobial substances.
N-Acetyl-L-Cysteine (NAC) is an antioxidant used to provide powerful support to the lungs and respiratory tract due to its ability to break up mucus and clear the respiratory passages.2* Human studies have shown NAC can significantly support immune system health and lung function during cold and flu season.27,28
This botanical may promote immune system health.* One double-blind, placebo-controlled study of 146 participants found that a garlic supplement was able to support immunity from November to February.29* A cell culture study investigated the effects of organosulfur compounds found in
garlic essential oil on SARS-CoV-2.30* Angiotensin-converting enzyme 2 (ACE2) protein in the human body serves as a receptor for SARS-CoV-2.* By blocking ACE2, garlic compounds may support immune health during exposure to this virus.* This is an interesting line of research scientists will hopefully undertake in humans in the future.
Citrus Bioflavonoid Complex
Citrus bioflavonoids are beneficial compounds derived from such fruits as oranges and lemons. Citrus bioflavonoids like hesperidin are able to maintain immunity.31-32* They work together synergistically with vitamin C to promote optimal health.*