is a patented, synergistic combination of two powerful botanical extracts (GymnePURE™ Gymnema sylvestre leaf and TinosPURE™ Tinospora cordifolia stem) that support healthy blood glucose and lipid metabolism; all critical metabolic health markers. OSA™ technology captures the most potent and bio-active parts of the plant to deliver superior health benefits such as optimizing the ratio of vital hormones leptin and adiponectin responsible for supporting healthy weight management. †


It is generally agreed that metabolic changes are on the rise among the adult population of the United States. According to a study examining the rate of metabolic changes between 1999 and 2010 published in the Journal of the American College of Cardiology, it was noted that certain factors including abdominal obesity might have profound effects on the body’s normal regulation of metabolic factors.

Gymnema sylvestre and Tinospora cordifolia are 2 traditional herbs used in Ayurvedic medicine for centuries. The combination of the 2 has been recently studied for the important roles they can play in metabolic health, already normal lipid metabolism, healthy weight management and already healthy blood pressure regulation.

LeptiPURE™ works in several ways to support the body’s metabolic functions. First, it can play important roles in supporting the leptin-to-adiponectin ratio in the body. Leptin and adiponectin are hormones involved in controlling hunger urges and fatty acid breakdown, respectively. Leptin acts on receptors in the hypothalamus to produce a feeling of satiety. Second, LeptiPURE™ may support the body’s already normal sugar absorption in the gut there. It can also support already normal glucose utilization by acting on enzymes involved in glucose and lipid metabolism such as phosphorylase, gluconeogenic enzymes, and sorbitol dehydrogenase. Finally, LeptiPURE™ may support the body’s normal digestion of fat and support the increased excretion of neutral sterols and acid steroids. In one clinical study, LeptiPURE™ was found to support several crucial blood biomarkers including Serum HbA1c and C-reactive protein, thus indicating its supportive roles in metabolic health.

To ensure optimal bioavailability, LeptiPURE™ utilizes OSA Technology. OSA™ is a patented extraction technology that captures the most potent and bioactive constituents of the plant to deliver superior health benefits compared to the standard botanical extract.

FORMULA (#5003)

Supplement Facts Serving Size 1 capsule


GymnePure 8X Gymnema sylvestre extract (leaf) & TinosPURE Tinospora cordifolia extract (stem)

Other Ingredients: Hydroxypropyl Methylcellulose (capsule).


Adults take 1 capsule or as directed by your health care practitioner


Soham Saha and Shyamasree Ghosh. Tinospora cordifolia: One plant, many roles. Anc Sci Life. 2012 Apr-Jun; 31(4): 151–159.

Amita Mishra, Shashank Kumar, and Abhay K. Pandey. Scientific Validation… Scientific World Journal. 2013; 2013: 292934.

Richard Nahas. Complementary and alternative medicine… Can Fam Physician. 2009 Jun; 55(6): 591–596. Ríos JL, Francini F, Schinella GR. Natural Products.. Planta Med. 2015 Aug;81(12-13):975-94.

Tiwari P, Mishra BN, Sangwan NS. Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant. Biomed Res Int. 2014; 2014:830285.

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